Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756547 | 0.80 | SLC1A3 (0.58) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL6006417 | 0.77 | SLC1A3 (0.61) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL12132457 | 0.77 | KDM4E (0.56) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL6006410 | 0.75 | SLC1A3 (0.55) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL20025843 | 0.75 | SLC1A3 (0.55) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL13951132 | 0.74 | SLC1A3 (0.54) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL6756542 | 0.73 | CYP3A4 (0.67) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL6006634 | 0.72 | CYP3A4 (0.69) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL4263470 | 0.71 | CYP3A4 (0.78) | SCN1ASCN2ASCN3ACYP3A4KDM4E | |
| SCHEMBL9468163 | 0.71 | SLC1A3 (0.64) | SCN1ASCN2ASCN3ACYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713473-B1 | 6-CARBAMATE-1,2,3,4-TETRAHYDROCARBAZOLE DERIVATIVES; AFFINITY FOR NEUROPEPTIDE Y RECEPTORS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1184373-A1 | TRICYCLIC COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |