Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.76 |
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756977 | 1.00 | MAOB (0.76) | MAOBMAOAPTGS1NFKB1MAPT | |
| SCHEMBL6756974 | 1.00 | MAOB (0.76) | MAOBMAOAPTGS1NFKB1MAPT | |
| SCHEMBL6755620 | 0.84 | MAOB (0.65) | MAOBMAOAPTGS1NFKB1MAPT | |
| SCHEMBL6755622 | 0.84 | MAOB (0.65) | MAOBMAOAPTGS1NFKB1MAPT | |
| SCHEMBL6755624 | 0.84 | MAOB (0.65) | MAOBMAOAPTGS1NFKB1MAPT | |
| SCHEMBL8060460 | 0.84 | MAOB (0.76) | MAOBMAOANFKB1MAPTPKM | |
| SCHEMBL8060458 | 0.84 | MAOB (0.76) | MAOBMAOANFKB1MAPTPKM | |
| SCHEMBL6757848 | 0.82 | MAOB (0.61) | MAOBMAOAPTGS1NFKB1LMNA | |
| SCHEMBL6757855 | 0.82 | MAOB (0.61) | MAOBMAOAPTGS1NFKB1LMNA | |
| SCHEMBL6757858 | 0.82 | MAOB (0.61) | MAOBMAOAPTGS1NFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | MAOB 1077/4885MAOA 1183/4885PTGS1 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.