SCHEMBL6757429

SCHEMBL6757429

CCCCNC(=O)c1cc2cc(N(Cc3cncn3Cc3ccc(C#N)cc3)C(=O)CCC3CCCC3)ccc2s1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 10/20 0.40
FNTB P49356 10/20 0.40
KCNH2 Q12809 2/20 0.40
PGGT1B P53609 2/20 0.40
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756404 0.92 CYP11B1 (0.42) FNTAFNTBKCNH2PGGT1BCYP11B1
SCHEMBL6602097 0.91 CYP11B1 (0.42) FNTAFNTBKCNH2PGGT1BCYP11B1
SCHEMBL6600292 0.90 CYP11B1 (0.41) FNTAFNTBKCNH2PGGT1BCYP11B1
SCHEMBL6757423 0.89 FNTA (0.41) FNTAFNTBKCNH2PGGT1B
SCHEMBL6756396 0.87 FNTA (0.41) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL6601239 0.87 FNTA (0.41) FNTAFNTBKCNH2PGGT1BCYP11B1
SCHEMBL6600830 0.84 FNTA (0.45) FNTAFNTBKCNH2PGGT1B
SCHEMBL6602232 0.83 FNTA (0.41) FNTAFNTBCYP11B1CYP11B2
SCHEMBL6759290 0.83 CYP11B1 (0.41) FNTAFNTBKCNH2PGGT1BCYP11B1
SCHEMBL6760840 0.83 CYP11B1 (0.40) FNTAFNTBKCNH2PGGT1BCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040204417-A1 Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins PIERRE FABRE MEDICAMENT (FR) 2004-10-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204417-A1 Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins CBR1, CBR3, HCCS FNTA 338/4885FNTB 215/4885KCNH2 2643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.