Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 7/20 | 0.50 |
| ▸ | MMP2 | P08253 | 7/20 | 0.50 |
| ▸ | MMP9 | P14780 | 7/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758174 | 1.00 | GSK3B (0.56) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6754336 | 0.91 | GSK3B (0.55) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6754332 | 0.91 | GSK3B (0.55) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6756808 | 0.91 | GSK3B (0.65) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6756807 | 0.91 | GSK3B (0.65) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6754391 | 0.87 | MAOB (0.58) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6754387 | 0.87 | MAOB (0.58) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6755701 | 0.87 | MAPT (0.52) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6755704 | 0.87 | MAPT (0.52) | GSK3BDYRK1AMEN1MAPTKMT2A | |
| SCHEMBL6759913 | 0.86 | DYRK1A (0.54) | GSK3BDYRK1AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | GSK3B 4671/4885DYRK1A 3409/4885MEN1 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.