SCHEMBL67587

SCHEMBL67587

O=C1CCSc2c(Cl)cc(Cl)cc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.54
ELOC Q15369 1/20 0.54
ELOB Q15370 1/20 0.54
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
HTT P42858 1/20 0.36
CA2 P00918 1/20 0.36
CES1 P23141 1/20 0.34
DNMT1 P26358 1/20 0.34
NOTUM Q6P988 1/20 0.32
MAPT P10636 4/20 0.32
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
POLB P06746 1/20 0.32
BLM P54132 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30543398 1.00 VHL (0.54) VHLELOCELOBMEN1KMT2A
SCHEMBL28387239 0.82 VHL (0.44) VHLELOCELOBMEN1KMT2A
SCHEMBL13890187 0.82 VHL (0.51) VHLELOCELOBMEN1KMT2A
SCHEMBL6605520 0.82 VHL (0.51) VHLELOCELOBMEN1KMT2A
SCHEMBL23360691 0.81 MEN1 (0.41) VHLELOCELOBMEN1KMT2A
SCHEMBL6605669 0.78 KDM4E (0.54) VHLELOCELOBMEN1KMT2A
SCHEMBL6605262 0.75 VHL (0.44) VHLELOCELOBMEN1KMT2A
SCHEMBL10464 0.74 MAPT (0.46) VHLELOCELOBMEN1KMT2A
SCHEMBL9635203 0.74 PARP10 (0.42) VHLELOCELOBMEN1KMT2A
SCHEMBL10364109 0.72 VHL (0.51) VHLELOCELOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
CN-116496261-A 4- (1H) -imidazole derivative and medical application thereof 中国人民解放军军事科学院军事医学研究院 2023-07-28 CN disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
EP-3950856-A1 PHOTOCURABLE INK COMPOSITION AND METHOD FOR IMAGE RECORDING FUJIFILM Corporation (JP) 2022-02-09 EP disclosed
US-20210395549-A1 PHOTOCURABLE INK COMPOSITION AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
US-20200199385-A1 ACTIVE ENERGY RAY CURABLE-TYPE INK JET INK, LIGHT SHIELDING FILM, AND METHOD OF MANUFACTURING LIGHT SHIELDING FILM FUJIFILM CORPORATION (JP) 2020-06-25 US disclosed
EP-2412768-B1 Inkjet ink composition, inkjet recording method, and printed material FUJIFILM CORP (JP) 2019-01-23 EP disclosed
US-9878560-B2 Inkjet recording method using nozzle arrays and printed material obtained by the inkjet recording method FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
US-9878560-B2 Inkjet recording method using nozzle arrays and printed material obtained by the inkjet recording method FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
EP-1283837-A1 NEW THIOCHROMANE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS AstraZeneca AB (SE) 2003-02-19 EP disclosed
WO-2001087879-A1 NEW THIOCHROMANE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS ASTRAZENECA AB (SE) 2001-11-22 WO disclosed
EP-0212428-B1 DIHYDROBENZO/B /THIOPHENES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS ANTIFUNGALS SCHERING CORPORATION (US) 1990-06-06 EP disclosed
US-4731364-A Dihydrobenzo(B)thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1988-03-15 US disclosed
EP-0212428-A1 Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1987-03-04 EP disclosed
EP-0054233-B1 NOVEL BENZO(B)THIOPHENES, BENZO(B)FURANS, THIOCHROMANS AND CHROMANS, PROCESSES FOR THEIR PREPARATION AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1986-09-24 EP disclosed
US-4468404-A MICROBIOCIDES SCHERING CORPORATION (US) 1984-08-28 US disclosed
US-4431816-A FUNGICIDES; BACTERICIDES SCHERING CORPORATION (US) 1984-02-14 US disclosed
US-4352808-A FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS SCHERING CORPORATION (US) 1982-10-05 US disclosed
EP-0054233-A1 Novel benzo(b)thiophenes, benzo(b)furans, thiochromans and chromans, processes for their preparation and antimicrobial compositions containing them SCHERING CORPORATION (US) 1982-06-23 EP disclosed