SCHEMBL6760847

SCHEMBL6760847

CSCC[C@H](NC(=O)c1[nH]c2ccc(NCc3cnc[nH]3)cc2c1-c1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 16/20 0.53
FNTB P49356 16/20 0.53
PGGT1B P53609 5/20 0.53
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757366 0.81 FNTA (0.50) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL6759370 0.78 FNTA (0.73) FNTAFNTBPGGT1B
SCHEMBL6754940 0.76 KMT2A (0.66) FNTAFNTBMEN1KMT2A
SCHEMBL6754945 0.76 KMT2A (0.66) FNTAFNTBMEN1KMT2A
SCHEMBL7258579 0.74 FNTA (0.55) FNTAFNTBPGGT1B
SCHEMBL6759252 0.72 FNTA (0.65) FNTAFNTBPGGT1B
SCHEMBL6756359 0.69 APOBEC3G (0.45) FNTAFNTBMEN1KMT2A
SCHEMBL6777267 0.68 FNTA (0.67) FNTAFNTBPGGT1B
SCHEMBL6777272 0.68 FNTA (0.67) FNTAFNTBPGGT1B
Trifluoroacetic Acid SCHEMBL6760834 0.68 FNTA (0.53) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040204417-A1 Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins PIERRE FABRE MEDICAMENT (FR) 2004-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204417-A1 Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins CBR1, CBR3, HCCS FNTA 338/4885FNTB 215/4885PGGT1B 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.