Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069289 | 0.83 | HDAC1 (0.47) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6387515 | 0.83 | HDAC1 (0.49) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6385635 | 0.82 | HDAC1 (0.51) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6387635 | 0.82 | HDAC1 (0.48) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6385831 | 0.78 | HDAC1 (0.51) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL1063809 | 0.78 | HDAC1 (0.65) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6388820 | 0.77 | MEN1 (0.51) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6385066 | 0.76 | HDAC1 (0.43) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6385726 | 0.76 | HDAC1 (0.52) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL6069165 | 0.75 | HDAC1 (0.50) | HDAC1HDAC3HDAC8HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162317-A1 | Mono-acylated o-phenylendiamines derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2004-08-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162317-A1 | Mono-acylated o-phenylendiamines derivatives | HDAC1, HDAC11, HDAC10 | HDAC1 1/4885HDAC3 12/4885HDAC8 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.