SCHEMBL6763753

SCHEMBL6763753

CN[C@@H](CCCNC(=N)NS(C)(=O)=O)C(=O)N1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F2 P00734 5/20 0.35
TGM2 P21980 2/20 0.32
KDM1A O60341 3/20 0.32
DPP4 P27487 2/20 0.32
DPP7 Q9UHL4 2/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
CPB2 Q96IY4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6766421 0.99 F2 (0.34) F2TGM2KDM1ADPP4DPP7
SCHEMBL6763798 0.84 DPP8 (0.40) F2DPP4DPP7
Hydrochloric Acid SCHEMBL6767738 0.83 DPP8 (0.39) F2DPP4DPP7
Hydrochloric Acid SCHEMBL6768393 0.83 DPP8 (0.39) F2DPP4DPP7
SCHEMBL13437118 0.80 DPP7 (0.38) F2DPP7CPB2
Hydrochloric Acid SCHEMBL6766649 0.80 DPP8 (0.43) DPP4DPP7
SCHEMBL7297872 0.79 DPP7 (0.41) DPP4DPP7
SCHEMBL7297865 0.79 DPP7 (0.41) DPP4DPP7
Hydrochloric Acid SCHEMBL6763834 0.78 DPP7 (0.40) DPP4DPP7
Hydrochloric Acid SCHEMBL6763831 0.78 DPP7 (0.40) DPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6716843-B2 INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV LES LABORATOIRES SERVIER (FR) 2004-04-06 US disclosed
US-20030087950-A1 New alpha-amino acid sulphonyl compounds LES LABORATOIRES SERVIER (FR) 2003-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087950-A1 New alpha-amino acid sulphonyl compounds DNPEP, DPP4, DPP7 F2 3756/4885TGM2 550/4885KDM1A 1366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.