Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL8406680 | 0.96 | — | — | |
| Lactic Acid SCHEMBL8406681 | 0.96 | TP53 (0.79) | — | |
| Lactic Acid SCHEMBL216082 | 0.96 | — | — | |
| Lactic Acid SCHEMBL21127 | 0.96 | — | — | |
| Lactic Acid SCHEMBL28443561 | 0.96 | — | — | |
| Lactic Acid SCHEMBL1264936 | 0.92 | — | — | |
| Lactic Acid SCHEMBL6118754 | 0.92 | TP53 (0.85) | — | |
| Lactic Acid SCHEMBL6259811 | 0.92 | — | — | |
| Lactic Acid SCHEMBL239851 | 0.92 | — | — | |
| Lactic Acid SCHEMBL896609 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136498-B | Novel liquid organopolysiloxanes and use thereof | 道康宁东丽株式会社 | 2017-06-20 | — | — | CN | disclosed |
| CN-103619914-B | Organopolysiloxane elastomers and utilization thereof | 道康宁东丽株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-103608384-B | Liquid organopolysiloxane and use thereof | 道康宁东丽株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-104136498-A | Novel liquid organopolysiloxanes and use thereof | DOW CORNING TORAY CO LTD | 2014-11-05 | — | — | CN | disclosed |
| CN-103619914-A | Novel organopolysiloxane elastomer and use therefor | DOW CORNING TORAY CO LTD | 2014-03-05 | — | — | CN | disclosed |
| CN-103608384-A | Novel liquid organopolysiloxane and use thereof | DOW CORNING TORAY CO LTD | 2014-02-26 | — | — | CN | disclosed |
| CN-102666663-A | Novel organopolysiloxane copolymer | DOW CORNING TORAY CO LTD | 2012-09-12 | — | — | CN | disclosed |
| US-20040071741-A1 | Use of silicone waxes containing ester functional groups for thickening oily media | RHONE-POULENC CHIMIE (FR) | 2004-04-15 | — | — | US | disclosed |