⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676423 | 1.00 | — | — | |
| SCHEMBL15509040 | 1.00 | — | — | |
| SCHEMBL17503296 | 0.97 | — | — | |
| SCHEMBL17503295 | 0.97 | — | — | |
| SCHEMBL811235 | 0.79 | — | — | |
| SCHEMBL811234 | 0.79 | — | — | |
| SCHEMBL12354183 | 0.78 | — | — | |
| SCHEMBL4451614 | 0.77 | — | — | |
| SCHEMBL4451616 | 0.77 | — | — | |
| SCHEMBL13936167 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484578-B | A kind of method of esomeprazole impurity preparation | 珠海润都制药股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-108484578-A | A kind of method prepared by esomeprazole impurity | 珠海润都制药股份有限公司 | 2018-09-04 | — | — | CN | disclosed |
| US-8957056-B2 | Migrastatin analogs in the treatment of cancer | SLOAN-KETTERING INSTIUTE FOR CANCER RESEARCH (US) | 2015-02-17 | — | — | US | disclosed |
| CN-103044402-B | Method for synthesizing esomeprazole sodium | KAMP PHARMACEUTICALS CO LTD | 2015-01-14 | — | — | CN | disclosed |
| US-8835693-B2 | Migrastatin analogs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140011844-A1 | MIGRASTATIN ANALOGS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-01-09 | — | — | US | disclosed |
| CN-103044402-A | Method for synthesizing esomeprazole sodium | KAMP PHARMACEUTICALS CO LTD | 2013-04-17 | — | — | CN | disclosed |
| US-8324284-B2 | Migrastatin analogs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2012-12-04 | — | — | US | disclosed |
| US-8202911-B2 | Migrastatin analog compositions and uses thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110281916-A1 | MIGRASTATIN ANALOGS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-11-17 | — | — | US | disclosed |
| US-20070037852-A1 | Migrastatin analogs and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-15 | — | — | US | disclosed |
| EP-1613603-A2 | MIGRASTATIN ANALOGS AND USES THEREOF | Sloan-Kettering Institute For Cancer Research (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2006001967-A2 | MIGRASTATIN ANALOGS IN THE TREATMENT OF CANCER | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2006-01-05 | — | — | WO | disclosed |
| EP-1608626-A1 | MIGRASTATIN ANALOG COMPOSITIONS AND USES THEREOF | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004087672-A1 | MIGRASTATIN ANALOG COMPOSITIONS AND USES THEREOF | CORNELL RESEARCH FOUNDATION, INC. (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087673-A2 | MIGRASTATIN ANALOGS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2004-10-14 | — | — | WO | disclosed |
| US-6043371-A | Organic compound synthesis | BALDWIN JACK EDWARD (GB) | 2000-03-28 | — | — | US | disclosed |
| EP-0899268-A2 | Process for the preparation of omeprazole and intermediate compounds | Baldwin, Jack Edward (GB) | 1999-03-03 | — | — | EP | disclosed |
| US-5625069-A | Process for preparing 2-cyano-3,5-dimethyl-4-methoxypyridine | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (CN) | 1997-04-29 | — | — | US | disclosed |
| US-5616713-A | Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1997-04-01 | — | — | US | disclosed |