⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL5013026 | 0.87 | STAT3 (0.32) | — | |
| Propionic Acid SCHEMBL28632737 | 0.78 | STAT3 (0.30) | — | |
| Propionic Acid SCHEMBL29556136 | 0.78 | STAT3 (0.30) | — | |
| SCHEMBL5337152 | 0.76 | PNP (0.35) | — | |
| Sulfuric Acid SCHEMBL28111784 | 0.76 | STAT3 (0.36) | — | |
| Sulfuric Acid SCHEMBL28081802 | 0.75 | STAT3 (0.35) | — | |
| SCHEMBL28854267 | 0.74 | GAA (0.35) | — | |
| SCHEMBL29156378 | 0.73 | STAT3 (0.34) | — | |
| SCHEMBL29288566 | 0.72 | STAT3 (0.33) | — | |
| SCHEMBL29288567 | 0.72 | STAT3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730666-B1 | INHIBITION OF GROWTH FACTOR TYROSINE KINASE RECEPTOR ACTIVITY, PARTICULARLY INHIBITION OF ANGIOGENESIS AND RELATED DISORDERS, TUMOR PROGRESSION AND GROWTH FACTOR RELATED SKELETAL DISORDERS, BY PORPHYRIN AND CORROLE COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-05-04 | — | — | US | claimed |