Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.42 |
| ▸ | CTRC | Q99895 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764576 | 0.91 | F2 (0.48) | F2PRSS2CTRCRECQL | |
| SCHEMBL6765120 | 0.88 | F2 (0.47) | F2PRSS2CTRCRECQL | |
| SCHEMBL6749317 | 0.85 | F2 (0.51) | F2PRSS2CTRC | |
| SCHEMBL6749509 | 0.84 | F2 (0.63) | F2PRSS2CTRCRECQL | |
| SCHEMBL6752152 | 0.83 | F2 (0.46) | F2PRSS2CTRCRECQL | |
| SCHEMBL6749611 | 0.81 | F2 (0.41) | F2PRSS2CTRC | |
| Hydrochloric Acid SCHEMBL6747723 | 0.81 | F2 (0.69) | F2PRSS2 | |
| SCHEMBL6747914 | 0.80 | F2 (0.64) | F2PRSS2CTRCRECQL | |
| SCHEMBL6750629 | 0.79 | F2 (0.65) | F2PRSS2CTRCRECQL | |
| Hydrochloric Acid SCHEMBL6747721 | 0.79 | F2 (0.49) | F2PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730783-B2 | REACTING AMINOGUANIDINE WITH CARBONYL COMPOUND TO FORM AMIDINOHYDRAZONE; REDUCTION; REACTING WITH ALKOXYAMINE; GUANIDINYLATION; ANTICOAGULANTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-05-04 | — | — | US | disclosed |
| US-6638931-B1 | Aminoguanidines and alkoxyguanidines as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-10-28 | — | — | US | disclosed |
| US-6235778-B1 | ANTICOAGULANTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-05-22 | — | — | US | disclosed |