Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 8/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082998 | 0.89 | TDP1 (0.46) | TDP1POLBRXFP1ALDH1A1LMNA | |
| SCHEMBL383586 | 0.89 | TDP1 (0.46) | TDP1POLBRXFP1ALDH1A1LMNA | |
| SCHEMBL5166341 | 0.88 | POLB (0.48) | TDP1POLBRXFP1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5170441 | 0.88 | TDP1 (0.45) | TDP1POLBRXFP1ALDH1A1LMNA | |
| SCHEMBL385258 | 0.85 | TDP1 (0.43) | TDP1POLBRXFP1ALDH1A1LMNA | |
| SCHEMBL5169422 | 0.85 | POLB (0.47) | TDP1POLBRXFP1ALDH1A1LMNA | |
| Fumaric Acid SCHEMBL383978 | 0.84 | POLB (0.42) | TDP1POLBRXFP1ALDH1A1LMNA | |
| SCHEMBL383831 | 0.84 | S1PR4 (0.43) | TDP1POLBRXFP1ALDH1A1LMNA | |
| Maleic Acid SCHEMBL383976 | 0.84 | POLB (0.42) | TDP1POLBRXFP1ALDH1A1LMNA | |
| SCHEMBL386525 | 0.84 | S1PR4 (0.44) | TDP1POLBRXFP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |