SCHEMBL6765463

SCHEMBL6765463

CC(C)(C)NC(=O)N1CCC(CC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 1.00
FNTB P49356 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6765636 0.92 FNTA (1.00) FNTAFNTB
SCHEMBL6638648 0.92 FNTA (0.88) FNTAFNTB
SCHEMBL6638181 0.91 FNTA (0.85) FNTAFNTB
SCHEMBL6769854 0.89 FNTA (1.00) FNTAFNTB
SCHEMBL6770570 0.88 FNTA (1.00) FNTAFNTB
SCHEMBL6634393 0.86 FNTA (1.00) FNTAFNTB
SCHEMBL6637425 0.85 FNTA (0.77) FNTAFNTB
SCHEMBL13935468 0.85 FNTA (0.92) FNTAFNTB
SCHEMBL13954623 0.84 FNTA (0.93) FNTAFNTB
SCHEMBL6636021 0.84 FNTA (0.75) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699872-B2 N-substituted urea inhibitors of farnesyl-protein transferase SCHERING CORPORATION 2004-03-02 US disclosed
US-20020119981-A1 Novel N-substituted urea inhibitors of farnesyl-protein transferase REMISZEWSKI STACY W (US) 2002-08-29 US disclosed
US-6358968-B1 FOR INHIBITING THE ABNORMAL GROWTH OF CELLS SCHERING CORPORATION 2002-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119981-A1 Novel N-substituted urea inhibitors of farnesyl-protein transferase FNTA, FNTB, UBTF FNTA 1/4885FNTB 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.