Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643914 | 1.00 | IDO1 (0.44) | IDO1CYP1A2CYP2A6TAAR1ACHE | |
| SCHEMBL18780575 | 1.00 | IDO1 (0.44) | IDO1CYP1A2CYP2A6TAAR1ACHE | |
| SCHEMBL4401171 | 0.82 | IDO1 (0.46) | IDO1CYP1A2CYP2A6TAAR1ACHE | |
| SCHEMBL14924458 | 0.81 | CYP1A2 (0.48) | IDO1CYP1A2CYP2A6TAAR1ACHE | |
| SCHEMBL14899900 | 0.78 | GFER (0.46) | ACHETDP1MAPTALDH1A1MEN1 | |
| SCHEMBL14080936 | 0.78 | CYP3A4 (0.38) | IDO1CYP1A2 | |
| SCHEMBL19649630 | 0.78 | IDO1 (0.42) | IDO1CYP2A6TAAR1AGXTALDH1A1 | |
| SCHEMBL775752 | 0.78 | IDO1 (0.42) | IDO1TAAR1ACHEAGXTLMNA | |
| SCHEMBL14204493 | 0.78 | TAAR1 (0.40) | IDO1CYP1A2CYP2A6TAAR1ALDH1A1 | |
| SCHEMBL40995 | 0.77 | TP53 (0.43) | IDO1TAAR1TDP1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| CN-109311907-B | Preparation method of high-purity prasugrel | 吉瑞工厂 | 2022-09-13 | — | — | CN | disclosed |
| US-RE46511-E1 | Fused pyrimidine derivatives for inhibition of tyrosine kinase activity | HANMI SCIENCE CO., LTD. (KR) | 2017-08-15 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9631181-B2 | Synthesis of prazole compounds | CODEXIS, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9631181-B2 | Synthesis of prazole compounds | CODEXIS, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160319252-A1 | SYNTHESIS OF PRAZOLE COMPOUNDS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-11-03 | — | — | US | disclosed |
| US-6746784-B2 | SUBSTITUTED OR UNSUBSTITUTED CYCLOHEXYLIDENEMETHINE GROUP COMPOUNDS WITH IMPROVED HOLE INJECTION PROPERTIES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2004-06-08 | — | — | US | disclosed |
| US-20020058156-A1 | Substituted or unsubstituted cyclohexylidenemethine group compounds with improved hole injection properties | SAMSUNG DISPLAY CO., LTD. (KR) | 2002-05-16 | — | — | US | disclosed |
| EP-0650487-A1 | NOVEL DIAZABICYCLOALKENES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994002479-A1 | NOVEL DIAZABICYCLOALKENES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-02-03 | — | — | WO | disclosed |
| US-4499149-A | ADHESION; HEAT RESISTANCE; PROTECTIVE COATINGS; SEMICONDUCTORS; POLYIMIDES | M&T CHEMICALS INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4480009-A | POLYIMIDE, POLYAMIDEIMIDE, OR POLY-HALF-AMIDE | M&T CHEMICALS INC. (US) | 1984-10-30 | — | — | US | disclosed |
| US-4395527-A | POLYIMIDES FROM AMINOPOLYSILOXANES | M & T CHEMICALS INC. (US) | 1983-07-26 | — | — | US | disclosed |
| EP-0054426-A2 | Improvements in or relating to siloxanes | M & T CHEMICALS, INC. (US) | 1982-06-23 | — | — | EP | disclosed |
| US-4125530-A | FROM 1,1-DIHALO-3,3,3-TRIFLUOROACETONE, BASE, AMMONIA AND A CARBOXALDEHYDE | MERCK & CO., INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4032522-A | ANTI-GOUT, ANTI-HYPERURICEMIC | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | IDO1 258/4885CYP1A2 53/4885CYP2A6 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.