Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | HTR2A | P28223 | 5/20 | 0.73 |
| ▸ | HTR1A | P08908 | 5/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | HTR1D | P28221 | 2/20 | 0.73 |
| ▸ | HTR1B | P28222 | 2/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
| ▸ | HTR7 | P34969 | 2/20 | 0.73 |
| ▸ | HTR6 | P50406 | 2/20 | 0.73 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.73 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.69 |
| ▸ | HTR2B | P41595 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375720 | 1.00 | CYP2D6 (1.00) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL8306922 | 0.91 | CYP2D6 (0.83) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL9329211 | 0.90 | CYP2D6 (0.81) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL5362738 | 0.88 | CYP2D6 (0.79) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL5368511 | 0.88 | CYP2D6 (0.79) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL5363947 | 0.88 | CYP2D6 (0.79) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL5360884 | 0.88 | CYP2D6 (0.79) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL5350306 | 0.88 | CYP2D6 (0.79) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL29899096 | 0.88 | CYP2D6 (0.78) | CYP2D6HTR2AHTR1ACYP1A2HTR1D | |
| SCHEMBL3812224 | 0.88 | CYP2D6 (0.78) | CYP2D6HTR2AHTR1ACYP1A2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220196684-A1 | METHOD FOR DETECTING OR MONITORING THE DEVELOPMENT OF A CHRONIC DEGENERATIVE DISEASE BY IMMUNOASSAY | PLL THERAPEUTICS (FR) | 2022-06-23 | — | — | US | claimed |
| EP-3948300-A1 | METHOD FOR DETECTING OR MONITORING THE DEVELOPMENT OF A CHRONIC DEGENERATIVE DISEASE BY IMMUNOASSAY | PolyNeuroS (FR) | 2022-02-09 | — | — | EP | claimed |
| WO-2020201332-A1 | METHOD FOR DETECTING OR MONITORING THE DEVELOPMENT OF A CHRONIC DEGENERATIVE DISEASE BY IMMUNOASSAY | POLYNEUROS (FR) | 2020-10-08 | — | — | WO | claimed |
| CN-106501409-B | A kind of urine metabolism marker identification method based on senile dementia | 王喜军 | 2019-09-24 | — | — | CN | claimed |
| EP-2986330-B1 | IMPLANTS FOR INDUCING SOFT AND HARD TISSUE INTEGRATION | NUMAT BIOMEDICAL S L (ES) | 2018-10-17 | — | — | EP | claimed |
| US-9849212-B2 | Implants for inducing soft and hard tissue integration | NUMAT BIOMEDICAL S.L. (ES) | 2017-12-26 | — | — | US | claimed |
| US-20160082147-A1 | IMPLANTS FOR INDUCING SOFT AND HARD TISSUE INTEGRATION | NUMAT BIOMEDICAL S.L. (ES) | 2016-03-24 | — | — | US | claimed |
| EP-2986330-A1 | IMPLANTS FOR INDUCING SOFT AND HARD TISSUE INTEGRATION | Numat Biomedical S.L. (ES) | 2016-02-24 | — | — | EP | claimed |
| WO-2014169959-A1 | IMPLANTS FOR INDUCING SOFT AND HARD TISSUE INTEGRATION | NUMAT BIOMEDICAL S.L. (ES) | 2014-10-23 | — | — | WO | claimed |
| US-8062648-B2 | Formulations containing melatonin, ginkgo biloba, and biotin | ASAT AG APPLIED SCIENCE & TECHNOLOGY (CH) | 2011-11-22 | — | — | US | claimed |
| EP-0566566-A1 | COMPOSITIONS AND METHODS FOR ALLEVIATING MENOPAUSAL SYMPTOMS. | APPLIED MED RES LTD (US) | 1993-10-27 | — | — | EP | claimed |
| WO-1992011855-A1 | COMPOSITIONS AND METHODS FOR ALLEVIATING MENOPAUSAL SYMPTOMS | APPLIED MEDICAL RESEARCH, LTD. (US) | 1992-07-23 | — | — | WO | claimed |
| EP-0214254-B1 | MELATONIN COMPOSITIONS AND USES THEREOF | CELLENA (CELL ENGINEERING) A.G. (CH) | 1992-06-17 | — | — | EP | claimed |
| EP-0472628-A1 | USE OF MELATONIN DERIVATIVES FOR EFFECTING CONTRACEPTION | APPLIED MEDICAL RESEARCH, LTD. (US) | 1992-03-04 | — | — | EP | claimed |
| WO-1990014084-A1 | USE OF MELATONIN DERIVATIVES FOR EFFECTING CONTRACEPTION | COHEN MICHAEL (NL) | 1990-11-29 | — | — | WO | claimed |
| US-4882137-A | MELATONIN | GENE LINK AUSTRALIA LIMITED (AU) | 1989-11-21 | — | — | US | claimed |
| US-4746674-A | Melatonin compositions and uses thereof | CELLENA (CELL ENGINEERING) AG (CH) | 1988-05-24 | — | — | US | claimed |
| EP-0246910-A2 | Coated veterinary implants | Hoechst Veterinär GmbH (DE) | 1987-11-25 | — | — | EP | claimed |
| EP-0229131-A1 | USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS | CELLENA (CELL ENGENEERING) A.G. (CH) | 1987-07-22 | — | — | EP | claimed |
| WO-1987000432-A2 | USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS | CELLENA (CELL ENGINEERING) A.G. (CH) | 1987-01-29 | — | — | WO | claimed |