Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504020 | 0.76 | GAA (0.33) | GAAMAPTATAD2ALDH1A1 | |
| SCHEMBL17329460 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL21847661 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL10226283 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL64635 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL15803217 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL774016 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL767777 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL14791302 | 0.72 | PNP (0.44) | MAPT | |
| SCHEMBL30100125 | 0.72 | PNP (0.44) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727059-B1 | ADMINISTERING A NUCLEOSIDE ANALOG THAT HAS A 3' HYDROXYL GROUP LOCATED ON THE C3' CARBON OF THE 2'-DEOXYRIBOSE, FOR EXAMPLE DUTP; FOR RETROID VIRUS INFECTIONS SUCH AS HIV; MIXTURE WITH REVERSE TRANSCRIPTASE INHIBITORS SUCH AS AZT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2004-04-27 | — | — | US | disclosed |