Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766464 | 0.96 | MAPK14 (0.47) | MAPK14 | |
| SCHEMBL6768647 | 0.93 | MAPK14 (0.50) | MAPK14 | |
| SCHEMBL6763896 | 0.91 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6766432 | 0.90 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL6768583 | 0.90 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL6767032 | 0.86 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL6766589 | 0.85 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL6619656 | 0.85 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6763928 | 0.84 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL6773320 | 0.83 | MAPK14 (0.62) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677337-B2 | RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, INFLAMMATORY BOWEL DISEASE, CACHEXIA, SEPTIC SHOCK, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | THE PROCTER & GAMBLE COMPANY | 2004-01-13 | — | — | US | claimed |