Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624604 | 1.00 | CACNA1C (0.33) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6621372 | 0.93 | CACNA1C (0.35) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6771850 | 0.93 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6624812 | 0.92 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6772792 | 0.92 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6626164 | 0.92 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6623238 | 0.92 | CACNA1C (0.33) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6771009 | 0.91 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6623408 | 0.90 | CACNA1C (0.33) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL6622380 | 0.89 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825187-B2 | CARBAPENEM DERIVATIVES SUBSTITUTED AT THE 2-POSITION WITH A SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP; USE AGAINST ANTIBIOTIC RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA, ENTEROCOCCI AND INFLUENZA VIRUS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-11-30 | — | — | US | disclosed |