Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6780186 | 0.86 | F10 (0.56) | F10F2MCHR1NR3C1NPC1 | |
| Hydrochloric Acid SCHEMBL6774963 | 0.86 | F10 (0.56) | F10F2MCHR1NR3C1NPC1 | |
| Hydrochloric Acid SCHEMBL6773951 | 0.85 | F10 (0.61) | F10F2MCHR1NR3C1NPC1 | |
| Hydrochloric Acid SCHEMBL6887808 | 0.85 | F10 (0.61) | F10F2MCHR1NR3C1NPC1 | |
| SCHEMBL6107968 | 0.82 | F10 (0.73) | F10F2 | |
| SCHEMBL6107570 | 0.82 | F10 (0.60) | F10F2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2981323 | 0.80 | F10 (0.59) | F10F2DEGS1LMNANR3C1 | |
| SCHEMBL2974502 | 0.80 | F10 (0.75) | F10F2DEGS1NR3C1 | |
| SCHEMBL6108954 | 0.80 | F10 (0.65) | F10F2TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL6106469 | 0.79 | F10 (0.64) | F10F2TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689780-B1 | PYRIDINE DERIVATIVES | ELI LILLY AND COMPANY | 2004-02-10 | — | — | US | disclosed |
| EP-1140905-B1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | LILLY CO ELI (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |