Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | STS | P08842 | 4/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108406 | 0.88 | F10 (0.58) | F10STSPTPN2PTPN1PTPN6 | |
| SCHEMBL6769439 | 0.88 | F10 (0.51) | F10STSPTPN2PTPN1PTPN6 | |
| SCHEMBL6106348 | 0.88 | F10 (0.51) | F10STSPTPN2PTPN1PTPN6 | |
| SCHEMBL6773664 | 0.86 | F10 (0.57) | F10STSPTPN2PTPN1PTPN6 | |
| SCHEMBL6106883 | 0.85 | F10 (0.49) | F10STSPTPN2PTPN1PTPN6 | |
| SCHEMBL6107829 | 0.85 | F10 (0.61) | F10STSPTPN2PTPN1PTPN6 | |
| SCHEMBL5384090 | 0.85 | F10 (0.71) | F10STSNR3C1 | |
| SCHEMBL6106396 | 0.83 | F10 (0.54) | F10STSPTPN2PTPN1PTPN6 | |
| Hydrochloric Acid SCHEMBL6772450 | 0.83 | F10 (0.70) | F10RAB9AMAPK1 | |
| SCHEMBL6108664 | 0.82 | F10 (0.63) | F10STSNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689780-B1 | PYRIDINE DERIVATIVES | ELI LILLY AND COMPANY | 2004-02-10 | — | — | US | disclosed |
| EP-1140905-B1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | LILLY CO ELI (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |