Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166232 | 0.97 | HDAC4 (0.41) | HDAC4HDAC6ALOX5TRPV1TP53 | |
| SCHEMBL5167475 | 0.89 | MAPT (0.40) | HDAC4HDAC6TRPV1TP53ALDH1A1 | |
| SCHEMBL6770520 | 0.88 | S1PR1 (0.44) | CASP3CASP7ALDH1A1S1PR4S1PR1 | |
| SCHEMBL5168391 | 0.87 | POLB (0.40) | HDAC4HDAC6TP53ALDH1A1S1PR1 | |
| SCHEMBL385258 | 0.86 | TDP1 (0.43) | HDAC4HDAC6TRPV1TP53CASP3 | |
| SCHEMBL6768979 | 0.86 | NAMPT (0.41) | TRPV1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5166925 | 0.86 | S1PR1 (0.43) | ALDH1A1S1PR4S1PR1S1PR3HPGD | |
| SCHEMBL5168050 | 0.85 | HDAC1 (0.47) | HDAC6 | |
| SCHEMBL5167470 | 0.84 | POLB (0.43) | ALDH1A1S1PR4S1PR1S1PR3MAPT | |
| SCHEMBL5169197 | 0.84 | POLB (0.45) | ALDH1A1S1PR4S1PR1S1PR3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | claimed |