Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.72 |
| ▸ | ESR1 | P03372 | 6/20 | 0.72 |
| ▸ | TTR | P02766 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.62 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.62 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780401 | 1.00 | ESR2 (0.72) | ESR2ESR1TTRALOX12ALOX15 | |
| SCHEMBL16441323 | 0.92 | ESR2 (0.76) | ESR2ESR1TTRALOX12ALOX15 | |
| SCHEMBL19696200 | 0.92 | ESR2 (0.76) | ESR2ESR1TTRALOX12ALOX15 | |
| SCHEMBL15297139 | 0.92 | ESR2 (0.57) | ESR2ESR1TTRALOX12ALOX15 | |
| Aus-131 SCHEMBL43648 | 0.84 | ESR2 (1.00) | ESR2ESR1TTRALOX12ALOX15 | |
| Aus-131 SCHEMBL29467332 | 0.84 | ESR2 (1.00) | ESR2ESR1TTRALOX12ALOX15 | |
| Aus-131 SCHEMBL43647 | 0.84 | ESR2 (1.00) | ESR2ESR1TTRALOX12ALOX15 | |
| Aus-131 SCHEMBL677723 | 0.84 | ESR2 (1.00) | ESR2ESR1TTRALOX12ALOX15 | |
| Aus-131 SCHEMBL2002128 | 0.84 | ESR2 (1.00) | ESR2ESR1TTRALOX12ALOX15 | |
| Aus-131 SCHEMBL17591903 | 0.80 | ESR2 (0.83) | ESR2ESR1TTRALOX12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173866-B2 | Compositions and products containing R-equol, and methods for their making | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2015-11-03 | — | — | US | disclosed |
| US-20120122967-A2 | COMPOSITIONS AND PRODUCTS CONTAINING R-EQUOL, AND METHODS FOR THEIR MAKING | AUSTRALIAN HEALTH & NUTRITION ASSOCIATION LIMITED (AU) | 2012-05-17 | — | — | US | disclosed |