Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL3411521 | 1.00 | — | — | |
| Lactic Acid SCHEMBL969329 | 1.00 | — | — | |
| Lactic Acid SCHEMBL28775523 | 0.96 | TP53 (0.79) | TP53TSHROR51E2SLC7A5 | |
| Lactic Acid SCHEMBL28835863 | 0.96 | TP53 (0.79) | TP53TSHROR51E2SLC7A5 | |
| Lactic Acid SCHEMBL25194 | 0.96 | — | — | |
| Lactic Acid SCHEMBL248090 | 0.96 | — | — | |
| Lactic Acid SCHEMBL838896 | 0.96 | — | — | |
| Lactic Acid SCHEMBL22341770 | 0.96 | — | — | |
| Lactic Acid SCHEMBL3776949 | 0.96 | TP53 (0.92) | TP53TSHROR51E2SLC7A5ALDH1A1 | |
| L-Lactic Acid SCHEMBL5921449 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113647666-B | Preparation method of heated cigarette | 江西中烟工业有限责任公司 | 2022-06-24 | — | — | CN | claimed |
| CN-113633011-B | Preparation method of granular heating cigarette | 江西中烟工业有限责任公司 | 2022-06-24 | — | — | CN | claimed |
| CN-113647666-A | Preparation method and application of special tobacco shreds for heating cigarettes | 江西中烟工业有限责任公司 | 2021-11-16 | — | — | CN | claimed |
| CN-113633011-A | Preparation method of tobacco particles of heated cigarettes | 江西中烟工业有限责任公司 | 2021-11-12 | — | — | CN | claimed |
| US-20130186829-A1 | BUFFERED COMPOSITIONS FOR DIALYSIS | ADVANCED RENAL TECHNOLOGIES (US) | 2013-07-25 | — | — | US | claimed |
| CN-102138932-A | Buffered compositions for dialysis | ADVANCED RENAL TECHNOLOGIES | 2011-08-03 | — | — | CN | claimed |
| EP-1124567-B2 | BUFFERED COMPOSITIONS FOR DIALYSIS | ADVANCED RENAL TECHNOLOGIES (US) | 2011-06-29 | — | — | EP | claimed |
| US-20100170849-A1 | BUFFERED COMPOSITIONS FOR DIALYSIS | ADVANCED RENAL TECHNOLOGIES (US) | 2010-07-08 | — | — | US | claimed |
| EP-1641473-B1 | BUFFERED COMPOSITIONS FOR DIALYSIS | ADVANCED RENAL TECHNOLOGIES (US) | 2010-04-14 | — | — | EP | claimed |
| US-7670491-B2 | Citrate concentrates comprising acetate and/or lactate | ADVANCED RENAL TECHNOLOGIES (US) | 2010-03-02 | — | — | US | claimed |
| CN-1863539-A | Buffered compositions for dialysis | ADVANCED RENAL TECHNOLOGIES (US) | 2006-11-15 | — | — | CN | claimed |
| EP-1641473-A1 | BUFFERED COMPOSITIONS FOR DIALYSIS | Advanced Renal Technologies (US) | 2006-04-05 | — | — | EP | claimed |
| EP-1124567-B1 | BUFFERED COMPOSITIONS FOR DIALYSIS | ADVANCED RENAL TECHNOLOGIES (US) | 2006-03-29 | — | — | EP | claimed |
| CN-1188136-C | Buffered composition for dialysis | ADVANCED RENAL TECHNOLOGIES (US) | 2005-02-09 | — | — | CN | claimed |
| WO-2005002599-A1 | BUFFERED COMPOSITIONS FOR DIALYSIS | ADVANCED RENAL TECHNOLOGIES (US) | 2005-01-13 | — | — | WO | claimed |
| US-20040060865-A1 | Citrate concentrates comprising acetate and/or lactate | ADVANCED RENAL TECHNOLOGIES | 2004-04-01 | — | — | US | claimed |
| US-6610206-B1 | Dialysate precursor compositions, which contains water, chloride, citrate, at least one buffering anion preferably selected from acetate and/or lactate, and at least one physiologically-acceptable cation | ADVANCED RENAL TECHNOLOGIES | 2003-08-26 | — | — | US | claimed |
| CN-1328467-A | Buffer composition for dialysis | ADVANCED RENAL TECHNOLOGIES (US) | 2001-12-26 | — | — | CN | claimed |
| EP-1124567-A2 | BUFFERED COMPOSITIONS FOR DIALYSIS | Advanced Renal Technologies (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000023086-A2 | BUFFERED COMPOSITIONS FOR DIALYSIS | ADVANCED RENAL TECHNOLOGIES (US) | 2000-04-27 | — | — | WO | claimed |