Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777207 | 0.93 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL6778807 | 0.92 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL6770168 | 0.89 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL6771190 | 0.88 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL6776073 | 0.88 | EDNRA (0.70) | EDNRA | |
| SCHEMBL6770777 | 0.87 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL6773347 | 0.86 | EDNRA (0.74) | EDNRA | |
| SCHEMBL6768186 | 0.84 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL6767698 | 0.84 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6777975 | 0.84 | EDNRA (0.79) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | claimed |
| US-6673824-B1 | HYPOTENSIVE AGENTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | disclosed |
| US-5514696-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 1996-05-07 | — | — | US | disclosed |