Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770199 | 1.00 | HDAC1 (0.42) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6770031 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6771219 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6770027 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6771216 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL4430921 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6765664 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6765666 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL4424612 | 0.92 | RARB (0.45) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL17299700 | 0.89 | HDAC1 (0.41) | HDAC1HDAC6HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683092-B1 | BREAST AND/OR PROSTATE CANCER | ALLERGAN, INC. | 2004-01-27 | — | — | US | disclosed |