Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27741826 | 0.89 | — | — | |
| Fluoride SCHEMBL21816906 | 0.89 | CA1 (0.57) | — | |
| SCHEMBL6560890 | 0.89 | — | — | |
| Ethyne SCHEMBL27932680 | 0.84 | CA1 (0.53) | — | |
| Ethylene SCHEMBL27518912 | 0.84 | CA1 (0.53) | — | |
| Hydrazine SCHEMBL27364485 | 0.84 | CA1 (0.53) | — | |
| Cyanide SCHEMBL27553732 | 0.80 | CA1 (0.50) | — | |
| SCHEMBL10337645 | 0.80 | BCL2L1 (0.55) | — | |
| SCHEMBL12562793 | 0.80 | BCL2L1 (0.55) | — | |
| SCHEMBL26821699 | 0.80 | BCL2L1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710080-B2 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20020198251-A1 | Substituted 2-dialkylaminoalkylbiphenyl derivatives | GRUENENTHAL GMBH (DE) | 2002-12-26 | — | — | US | disclosed |