Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340637 | 0.94 | PDE5A (0.63) | PDE5APDE6C | |
| SCHEMBL6332547 | 0.90 | PDE5A (0.66) | PDE5APDE6C | |
| SCHEMBL5595647 | 0.89 | PDE5A (0.91) | PDE5APDE6C | |
| SCHEMBL6334564 | 0.87 | PDE5A (0.71) | PDE5APDE6C | |
| SCHEMBL5595245 | 0.87 | PDE5A (0.77) | PDE5APDE6C | |
| SCHEMBL6330401 | 0.85 | PDE5A (0.76) | PDE5APDE6C | |
| SCHEMBL6338578 | 0.85 | PDE5A (0.76) | PDE5APDE6C | |
| SCHEMBL6334207 | 0.85 | PDE5A (0.70) | PDE5APDE6C | |
| SCHEMBL6330919 | 0.85 | PDE5A (0.70) | PDE5APDE6C | |
| SCHEMBL6338754 | 0.85 | PDE5A (0.69) | PDE5APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723719-B1 | DYSMENORRHOEA, BENIGN PROSTATIC HYPERPLASIA (BPH), BLADDER OUTLET OBSTRUCTION, INCONTINENCE, AGINA, CONGESTIVE HEART FAILURE, ATHEROSCLEROSIS; HYPOTENSIVE AND ANTIALLERGEN AGENTS | PFIZER INC | 2004-04-20 | — | — | US | disclosed |