Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3152273 | 1.00 | RXFP1 (0.50) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL7489539 | 1.00 | RXFP1 (0.50) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL481167 | 0.94 | RXFP1 (0.51) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL481166 | 0.94 | RXFP1 (0.51) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2569219 | 0.93 | RXFP1 (0.51) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2572320 | 0.93 | RXFP1 (0.51) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2572324 | 0.93 | RXFP1 (0.51) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL3159875 | 0.93 | RXFP1 (0.51) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL20807625 | 0.92 | RXFP1 (0.52) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL479601 | 0.91 | RXFP1 (0.49) | RXFP1SMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762180-B1 | Substituted indolines which inhibit receptor tyrosine kinases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-07-13 | — | — | US | disclosed |