Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771940 | 0.89 | EDNRB (0.66) | EDNRAEDNRB | |
| SCHEMBL6767779 | 0.88 | EDNRB (0.70) | EDNRAEDNRB | |
| SCHEMBL6772817 | 0.87 | EDNRB (0.68) | EDNRAEDNRB | |
| SCHEMBL6772824 | 0.86 | EDNRB (0.67) | EDNRAEDNRB | |
| SCHEMBL6777719 | 0.85 | EDNRA (0.74) | EDNRAEDNRB | |
| SCHEMBL6771570 | 0.85 | EDNRA (0.65) | EDNRAEDNRB | |
| SCHEMBL6768276 | 0.84 | EDNRB (0.72) | EDNRAEDNRB | |
| SCHEMBL6767145 | 0.83 | EDNRB (0.68) | EDNRAEDNRB | |
| SCHEMBL6778007 | 0.83 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6767611 | 0.83 | EDNRB (0.67) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | claimed |
| US-6673824-B1 | HYPOTENSIVE AGENTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | disclosed |