Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL512608 | 0.99 | HSD17B2 (0.98) | HSD17B2 | |
| SCHEMBL12687971 | 0.90 | HSD17B2 (1.00) | HSD17B2 | |
| SCHEMBL512945 | 0.90 | HSD17B2 (1.00) | HSD17B2 | |
| SCHEMBL512773 | 0.87 | HSD17B2 (1.00) | HSD17B2 | |
| SCHEMBL511895 | 0.87 | HSD17B2 (1.00) | HSD17B2 | |
| SCHEMBL511964 | 0.87 | HSD17B2 (1.00) | HSD17B2 | |
| SCHEMBL7048359 | 0.87 | HSD17B2 (1.00) | HSD17B2 | |
| Hydrochloric Acid SCHEMBL513279 | 0.86 | HSD17B2 (0.98) | HSD17B2 | |
| SCHEMBL511942 | 0.84 | HSD17B2 (0.73) | HSD17B2 | |
| SCHEMBL512877 | 0.82 | HSD17B2 (0.77) | HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784167-B2 | TREATING OSTEOPOROSIS, OSTEOPENIA, OVARIAN CANCER, BREAST CANCER, ENDOMETRIAL CANCER, ENDOMETRIOSIS, PROSTATE CANCER, ACNE, ANDROGEN-DEPENDENT HAIR LOSS, NON-INSULIN-DEPENDENT DIABETES MELLITUS, OR HYPERCHOLESTEROLEMIA. | BAYER PHARMACEUTICALS CORPORATION | 2004-08-31 | — | — | US | claimed |