Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474917 | 0.96 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6769137 | 0.92 | PDE4A (0.46) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6772615 | 0.87 | TLR7 (0.43) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6775579 | 0.86 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6768490 | 0.82 | PDE4A (0.38) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6706658 | 0.81 | PDE4A (0.45) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6773704 | 0.81 | PDE4A (0.41) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6481387 | 0.81 | PDE4B (0.43) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6825700 | 0.78 | PDE4A (0.45) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6482019 | 0.77 | PDE4A (0.47) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043324-B1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEM CORP (JP) | 2004-06-16 | — | — | EP | claimed |
| US-6734187-B1 | ANTIASTHMATIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-05-11 | — | — | US | claimed |
| EP-1043324-A1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | claimed |
| EP-1043324-B1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEM CORP (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6734187-B1 | ANTIASTHMATIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-05-11 | — | — | US | disclosed |
| EP-1043324-A1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |