Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20242116 | 0.88 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL4415617 | 0.86 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3391894 | 0.84 | SMN1; SMN2 (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3395527 | 0.84 | SMN1; SMN2 (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3394073 | 0.81 | MGAM (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3394079 | 0.81 | MGAM (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11301310 | 0.80 | CA1 (0.33) | TSHRCA1CA2ALDH1A1 | |
| SCHEMBL7888718 | 0.79 | TSHR (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL16256492 | 0.79 | TSHR (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3397370 | 0.78 | CA1 (0.34) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127119-B2 | Polycarbonate compositions having improved thermal dimensional stability and high refractive index | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-09-08 | — | — | US | disclosed |
| US-8064140-B2 | Transparent articles prepared from thermoplastic compositions having low birefringence | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-11-22 | — | — | US | disclosed |
| US-20110071261-A1 | TRANSPARENT ARTICLES PREPARED FROM THERMOPLASTIC COMPOSITIONS HAVING LOW BIREFRINGENCE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-03-24 | — | — | US | disclosed |