Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.37 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138895 | 0.78 | HDAC1 (0.51) | HDAC8HDAC6HDAC1ALDH1A1HPGD | |
| SCHEMBL6138998 | 0.78 | HDAC1 (0.51) | HDAC8HDAC6HDAC1ALDH1A1HPGD | |
| SCHEMBL6138450 | 0.78 | HDAC1 (0.51) | HDAC8HDAC6HDAC1ALDH1A1HPGD | |
| SCHEMBL6139008 | 0.78 | HDAC1 (0.51) | HDAC8HDAC6HDAC1ALDH1A1HPGD | |
| SCHEMBL6138539 | 0.76 | HDAC8 (0.52) | HDAC8HDAC6HDAC1ALDH1A1HDAC3 | |
| SCHEMBL6812985 | 0.72 | HDAC2 (0.50) | HDAC8HDAC6HDAC1HDAC3HDAC11 | |
| SCHEMBL6812978 | 0.72 | HDAC2 (0.50) | HDAC8HDAC6HDAC1HDAC3HDAC11 | |
| Hydrochloric Acid SCHEMBL6813385 | 0.72 | HRH3 (0.47) | HDAC8HDAC6HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6813384 | 0.72 | HRH3 (0.47) | HDAC8HDAC6HDAC1ALDH1A1 | |
| SCHEMBL6813413 | 0.70 | HDAC1 (0.42) | HDAC8HDAC6HDAC1HDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770644-B1 | Hydroxamic acid derivatives, process for the production thereof and drug containing the same as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |