Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARA | Q07869 | 8/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138899 | 0.81 | HDAC1 (0.60) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL6812985 | 0.76 | HDAC2 (0.50) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL6812978 | 0.76 | HDAC2 (0.50) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL6809455 | 0.75 | HSD17B10 (0.48) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL6809450 | 0.75 | HSD17B10 (0.48) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL6817795 | 0.73 | HDAC2 (0.47) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL6817789 | 0.73 | HDAC2 (0.47) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL2839404 | 0.72 | HDAC4 (0.60) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL29355433 | 0.69 | HDAC6 (1.00) | HDAC8HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL10361645 | 0.69 | HDAC6 (1.00) | HDAC8HDAC6HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770644-B1 | Hydroxamic acid derivatives, process for the production thereof and drug containing the same as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |