Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.65 |
| ▸ | NPY1R | P25929 | 3/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773850 | 1.00 | NPY5R (0.65) | NPY5RNPY1RDRD2ADRA2CTP53 | |
| SCHEMBL2865412 | 0.90 | NPY5R (0.72) | NPY5RNPY1RDRD2ADRA2CTP53 | |
| SCHEMBL14020738 | 0.84 | NPY5R (0.65) | NPY5RNPY1RDRD2ADRA2CTP53 | |
| SCHEMBL14020732 | 0.84 | NPY5R (0.65) | NPY5RNPY1RDRD2ADRA2CTP53 | |
| SCHEMBL5849554 | 0.83 | MEN1 (0.57) | NPY5RMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL5848417 | 0.83 | MEN1 (0.57) | NPY5RMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL18230239 | 0.83 | NPY5R (0.64) | NPY5RNPY1RDRD2ADRA2CTP53 | |
| SCHEMBL8888802 | 0.78 | NPY5R (0.64) | NPY5RNPY1RTSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30887942 | 0.78 | TP53 (1.00) | NPY5RNPY1RDRD2ADRA2CTP53 | |
| SCHEMBL3851236 | 0.78 | GBA1 (0.79) | NPY5RMEN1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683055-B1 | GUANIDINE OR AMIDINE TERMINED PEPTIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |