Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774355 | 1.00 | ACACB (0.47) | ACACBCNR2CNR1NAMPTLIPE | |
| SCHEMBL6778331 | 0.89 | TACR1 (0.45) | ACACBNAMPTLIPETACR1 | |
| SCHEMBL6778334 | 0.89 | TACR1 (0.45) | ACACBNAMPTLIPETACR1 | |
| SCHEMBL6783908 | 0.89 | TACR1 (0.45) | ACACBNAMPTLIPETACR1 | |
| SCHEMBL6778653 | 0.84 | GRIN2B (0.46) | SMN1; SMN2GRIN2B | |
| SCHEMBL6777723 | 0.84 | PRMT5 (0.48) | NAMPTPRMT5WDR77TACR1GRIN2B | |
| SCHEMBL6778660 | 0.84 | GRIN2B (0.46) | SMN1; SMN2GRIN2B | |
| SCHEMBL6774773 | 0.84 | PRMT5 (0.48) | NAMPTPRMT5WDR77TACR1GRIN2B | |
| SCHEMBL6774775 | 0.84 | PRMT5 (0.48) | NAMPTPRMT5WDR77TACR1GRIN2B | |
| SCHEMBL6586144 | 0.81 | ACACB (0.50) | ACACBCNR2CNR1NAMPTPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831078-B1 | 3-aryl substituted having halo or alkylhalo groups; anxiety, epilepsy; presurgery muscle relaxant | VERNALIS RESEARCH LIMITED (GB) | 2004-12-14 | — | — | US | disclosed |
| EP-1049670-B1 | AZETIDINECARBOXAMIDE DERIVATIVES FOR TREATING CNS DISORDERS | VERNALIS RES LTD (GB) | 2002-07-17 | — | — | EP | disclosed |