Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777551 | 0.90 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6285260 | 0.89 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL6773786 | 0.86 | TLR7 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6096443 | 0.86 | TLR7 (0.53) | TLR7TLR8NUDT1 | |
| SCHEMBL6773932 | 0.83 | GRIA1 (0.38) | TLR7GRIA1 | |
| SCHEMBL6094673 | 0.83 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL6783392 | 0.83 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL5030248 | 0.83 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL6776957 | 0.82 | TLR7 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL4793853 | 0.82 | TLR8 (0.42) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |