Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167470 | 0.99 | POLB (0.43) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL6770520 | 0.95 | S1PR1 (0.44) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL3509370 | 0.90 | S1PR1 (0.41) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL3509408 | 0.90 | S1PR1 (0.41) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL5166341 | 0.90 | POLB (0.48) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL5169197 | 0.90 | POLB (0.45) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL385369 | 0.89 | POLB (0.42) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL5168929 | 0.89 | POLB (0.42) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL3082998 | 0.89 | TDP1 (0.46) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL383586 | 0.89 | TDP1 (0.46) | POLBTDP1ALDH1A1LMNAPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | claimed |