Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6541293 | 0.99 | KCNK9 (0.54) | KCNK9NR1H4KCNK3PPARGPPARD | |
| SCHEMBL12131818 | 0.83 | F10 (0.53) | — | |
| SCHEMBL10178439 | 0.81 | F10 (0.43) | KCNK9KCNK3PLAU | |
| SCHEMBL6542489 | 0.81 | NR1H4 (0.69) | KCNK9NR1H4KCNK3MEN1ALDH1A1 | |
| SCHEMBL890957 | 0.81 | F10 (0.60) | — | |
| Hydrochloric Acid SCHEMBL6542009 | 0.81 | NR1H4 (0.78) | KCNK9NR1H4PPARGPPARDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6542404 | 0.80 | CA1 (0.48) | KCNK9NR1H4KCNK3PPARGPPARD | |
| SCHEMBL6541256 | 0.77 | KCNK9 (0.45) | KCNK9NR1H4KCNK3PPARGPPARD | |
| SCHEMBL6541251 | 0.77 | KCNK9 (0.45) | KCNK9NR1H4KCNK3PPARGPPARD | |
| SCHEMBL13762080 | 0.77 | KCNK9 (0.76) | KCNK9NR1H4KCNK3PPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677369-B2 | CARBOXIMIDAMIDE DERIVATIVE ANTICOAGULANTS INHIBIT FACTOR XA | ELI LILLY AND COMPANY | 2004-01-13 | — | — | US | claimed |