SCHEMBL6774754

SCHEMBL6774754

CC1CC(C(=O)Cl)CCN1C(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.44
HPGD P15428 1/20 0.43
RECQL P46063 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
GPR119 Q8TDV5 1/20 0.40
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
PTPN6 P29350 1/20 0.38
SETD7 Q8WTS6 1/20 0.37
STS P08842 4/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16680564 0.88 HSD17B10 (0.53) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL31069004 0.88 HSD17B10 (0.53) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL31068869 0.88 HSD17B10 (0.44) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL23694162 0.88 HSD17B10 (0.44) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL16680566 0.88 HSD17B10 (0.53) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL23694159 0.88 HSD17B10 (0.44) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL15491795 0.88 HSD17B10 (0.44) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL24927723 0.88 HSD17B10 (0.53) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL31001881 0.88 HSD17B10 (0.53) HSD17B10HPGDRECQLCHRM2CHRM1
SCHEMBL2072006 0.88 HSD17B10 (0.53) HSD17B10HPGDRECQLCHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688741-A1 COMPOUNDS FOR TREATING FIBROTIC DISEASES Meta-Immune, Inc. (KR) 2026-02-11 EP disclosed
WO-2024249867-A1 COMPOUNDS FOR TREATING FIBROTIC DISEASES AM SCIENCES (KR) 2024-12-05 WO disclosed
US-6689780-B1 PYRIDINE DERIVATIVES ELI LILLY AND COMPANY 2004-02-10 US disclosed
EP-1140905-B1 HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA LILLY CO ELI (US) 2003-05-14 EP disclosed
EP-1140905-A1 HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA ELI LILLY AND COMPANY (US) 2001-10-10 EP disclosed
WO-2000039117-A1 HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa ELI LILLY AND COMPANY (US) 2000-07-06 WO disclosed