Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 3/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779530 | 0.91 | SCN4A (0.52) | SCN4AERBB2HSPB1SCN9ATRPA1 | |
| SCHEMBL6779765 | 0.83 | SCN9A (0.54) | SCN4AERBB2SCN9AALDH1A1MAPT | |
| SCHEMBL1385301 | 0.82 | SCN4A (0.51) | SCN4ASCN9AALDH1A1GAAMAPT | |
| SCHEMBL15418939 | 0.82 | PARP10 (0.45) | SCN4AERBB2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL12096338 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1GAAMAPT | |
| SCHEMBL1386893 | 0.77 | SCN4A (0.42) | SCN4AERBB2HSPB1SCN9AMET | |
| SCHEMBL989177 | 0.77 | CA12 (0.42) | SCN4AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3366879 | 0.76 | SCN4A (0.41) | SCN4AERBB2HSPB1SCN9AMET | |
| SCHEMBL28052513 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1MAPT | |
| SCHEMBL3103824 | 0.76 | NOTUM (0.43) | ALDH1A1GAATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737418-B2 | CENTRAL NERVOUS SYSTEM DISORDERS; ANTICONVULSANTS | EURO-CELTIQUE S.A. (LU) | 2004-05-18 | — | — | US | disclosed |
| US-6414011-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | EURO-CELTIQUE S.A. (LU) | 2002-07-02 | — | — | US | disclosed |