Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784803 | 0.91 | PPARA (0.41) | ALDH1A1MEN1GAAKMT2AHCRTR2 | |
| SCHEMBL6779567 | 0.87 | PPARA (0.45) | ALDH1A1MEN1GAAKMT2AHCRTR2 | |
| SCHEMBL6774413 | 0.84 | PPARA (0.33) | ALDH1A1MEN1GAAKMT2ANPC1 | |
| SCHEMBL6784863 | 0.81 | PPARA (0.55) | ALDH1A1MEN1GAAKMT2AHCRTR2 | |
| SCHEMBL6781086 | 0.81 | PPARA (0.41) | ALDH1A1MEN1GAAKMT2APPARA | |
| SCHEMBL6780618 | 0.81 | PPARA (0.44) | HCRTR2RAB9APPARALMNAPPARG | |
| Hydrochloric Acid SCHEMBL6779016 | 0.80 | PPARA (0.54) | ALDH1A1MEN1GAAKMT2AHCRTR2 | |
| SCHEMBL6780585 | 0.77 | PPARA (0.38) | MEN1KMT2AHCRTR2PPARALMNA | |
| SCHEMBL6780911 | 0.76 | PPARA (0.47) | ALDH1A1MEN1GAAKMT2AHCRTR2 | |
| SCHEMBL4887402 | 0.76 | MEN1 (0.34) | ALDH1A1MEN1KMT2AHCRTR2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176445-A1 | Propionic acid derivatives | BAYER PHARMACEUTICALS CORPORATION | 2004-09-09 | — | — | US | disclosed |
| US-6750236-B2 | CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20030187041-A1 | Propionic acid derivatives | URBAHNS KLAUS (DE) | 2003-10-02 | — | — | US | disclosed |
| US-6548538-B2 | Potent peroxisome proliferator activated receptor (PPAR)-alpha-activating compounds; propionic acid 2-subsituted with an N-(phenylaminocarbonylalkyl), N-(2-furanylmethyl)aminoalkylphenyl group | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-15 | — | — | US | disclosed |
| US-20030032671-A1 | Propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187041-A1 | Propionic acid derivatives | PPARA, PPARD, PPARG | ALDH1A1 257/4885MEN1 4797/4885GAA 1063/4885 |
| US-20030032671-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | ALDH1A1 550/4885MEN1 4851/4885GAA 1680/4885 |
| US-20040176445-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | ALDH1A1 550/4885MEN1 4851/4885GAA 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.