SCHEMBL6775312

SCHEMBL6775312

COC(=O)C(CC(C)C)NC(=O)c1ccc(NCc2c[nH]cn2)cc1-c1ccccc1C

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FNTA P49354 14/20 0.59
PGGT1B P53609 13/20 0.59
FNTB P49356 12/20 0.59
TDP1 Q9NUW8 1/20 0.51
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
BCL2L1 Q07817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6775315 1.00 FNTA (0.59) FNTAPGGT1BFNTBTDP1TAS1R3
SCHEMBL16136628 0.92 FNTA (0.71) FNTAPGGT1BFNTB
SCHEMBL7608404 0.92 FNTA (0.71) FNTAPGGT1BFNTB
Hydrochloric Acid SCHEMBL6776199 0.91 FNTA (0.70) FNTAPGGT1BFNTB
SCHEMBL17548781 0.91 FNTA (0.55) FNTAPGGT1BFNTBTDP1MEN1
SCHEMBL10018886 0.90 FNTA (0.66) FNTAPGGT1BFNTBTDP1TAS1R3
SCHEMBL6775184 0.83 FNTA (0.69) FNTAPGGT1BFNTB
SCHEMBL4280385 0.81 FNTA (0.78) FNTAPGGT1BFNTBTDP1BCL2L1
SCHEMBL20564402 0.81 FNTA (0.61) FNTAPGGT1BFNTBTDP1MEN1
SCHEMBL6782079 0.78 FNTA (0.63) FNTAPGGT1BFNTBTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014160729-A1 COMPOSITION AND METHOD FOR TREATING CANCER CELLWORKS RESEARCH INDIA PVT. LTD (IN) 2014-10-02 WO disclosed
US-6693123-B2 (4-(3-PYRIDYLAMINOMETHYLENE)-2-PHENYLBENZOYL)-N -METHYLMETHIONINE, METHYL ESTER FOR EXAMPLE; RESTENOSIS, HYPERPLASIA UNIVERSITY OF PITTSBURGH 2004-02-17 US disclosed
US-20020193596-A1 Inhibitors of protein isoprenyl transferases UNIVERSITY OF PITTSBURGH (US) 2002-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193596-A1 Inhibitors of protein isoprenyl transferases LANCL1, FNTB, DHCR7 FNTA 20/4885PGGT1B 1021/4885FNTB 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.