⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran-3-Carbaldehyde SCHEMBL25907361 | 1.00 | — | — | |
| Tetrahydrofuran-3-Carbaldehyde SCHEMBL21581981 | 1.00 | — | — | |
| Tetrahydrofuran-3-Carbaldehyde SCHEMBL28110770 | 0.97 | — | — | |
| Tetrahydrofuran-3-Carbaldehyde SCHEMBL28643418 | 0.97 | — | — | |
| Tetrahydrofuran-3-Carbaldehyde SCHEMBL28331049 | 0.91 | — | — | |
| SCHEMBL10652149 | 0.87 | — | — | |
| SCHEMBL1942189 | 0.84 | — | — | |
| SCHEMBL98249 | 0.84 | — | — | |
| SCHEMBL1942816 | 0.84 | — | — | |
| SCHEMBL16624 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1892 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120157637-A | Preparation system and method of 3-methyltetrahydrofuran | 中化学科学技术研究有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-119565613-A | Composite catalyst for synthesizing tetrahydrofuran-3-methanol and method for synthesizing tetrahydrofuran-3-methanol by using composite catalyst | 重庆建峰新材料有限责任公司 | 2025-03-07 | — | — | CN | claimed |
| CN-116354909-B | Synthesis method of 3-iminomethyl tetrahydrofuran | 山东海利尔化工有限公司 | 2025-02-11 | — | — | CN | claimed |
| EP-4013755-B1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2025-01-08 | — | — | EP | claimed |
| CN-110914271-B | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-12-10 | — | — | CN | claimed |
| WO-2024119028-A1 | SUBSTITUTED QUINOLINE DERIVATIVES HAVING SOS1 INHIBITION ACTIVITIES AND USES THEREOF | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-06-06 | — | — | WO | claimed |
| WO-2024114814-A1 | JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | ONQUALITY PHARMACEUTICALS CHINA LTD (CN) | 2024-06-06 | — | — | WO | claimed |
| CN-117070484-A | Carbonyl reductase mutant and preparation and optical purity determination method of optical pure 3-hydroxytetrahydrofuran | 福州大学 | 2023-11-17 | — | — | CN | claimed |
| CN-116903835-A | Polyester containing acetal structure and preparation method thereof | 大连理工大学 | 2023-10-20 | — | — | CN | claimed |
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | claimed |
| US-5840928-A | Method for production of 3-formyl-tetrahydrofuran | MITSUI CHEMICALS, INC. (JP) | 1998-11-24 | — | — | US | claimed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0795552-A1 | A method for production of 3-formyl-tetrahydrofuran | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-09-17 | — | — | EP | claimed |
| JP-H09501913-A | — | — | 1997-02-25 | — | — | JP | claimed |
| EP-0738154-A1 | N-TERMINUS MODIFIED ANALOGS OF LHRH | Abbott Laboratories (US) | 1996-10-23 | — | — | EP | claimed |
| EP-0738154-A4 | N-TERMINUS MODIFIED ANALOGS OF LHRH | ABBOTT LAB (US) | 1996-04-12 | — | — | EP | claimed |
| US-5502035-A | N-terminus modified analogs of LHRH | TAP HOLDINGS INC. (US) | 1996-03-26 | — | — | US | claimed |
| WO-1995004541-A1 | N-TERMINUS MODIFIED ANALOGS OF LHRH | ABBOTT LABORATORIES (US) | 1995-02-16 | — | — | WO | claimed |
| US-4292246-A | ISOMERIZATION OF A 4,5-DIHYDRO-1,3-DIOXEPINE BY HEATING WITH CATALYTIC O-TOLUIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | claimed |