Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776069 | 1.00 | PPARA (0.31) | PPARASLC22A12 | |
| SCHEMBL6777053 | 0.91 | LATS1 (0.31) | — | |
| SCHEMBL6776575 | 0.83 | PPARA (0.37) | PPARA | |
| SCHEMBL6776581 | 0.83 | PPARA (0.37) | PPARA | |
| SCHEMBL6774046 | 0.83 | SLC22A12 (0.33) | PPARASLC22A12 | |
| SCHEMBL6774058 | 0.83 | SLC22A12 (0.33) | PPARASLC22A12 | |
| SCHEMBL6774862 | 0.79 | LATS1 (0.31) | — | |
| SCHEMBL6774859 | 0.79 | LATS1 (0.31) | — | |
| SCHEMBL6775213 | 0.77 | MAPK1 (0.38) | PPARA | |
| SCHEMBL6775208 | 0.77 | MAPK1 (0.38) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821994-B2 | A PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR REGULATOR, AN OXAZOL-4-YL-METHYLFURAN-2-YL-2-PROPENYLTHIO- OR SULFONYL- OR SULFINYL-ACETIC ACID OR METHYL ESTER | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-23 | — | — | US | claimed |
| US-20030225145-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2003-12-04 | — | — | US | claimed |
| EP-1122255-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-08-08 | — | — | EP | claimed |
| US-6821994-B2 | A PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR REGULATOR, AN OXAZOL-4-YL-METHYLFURAN-2-YL-2-PROPENYLTHIO- OR SULFONYL- OR SULFINYL-ACETIC ACID OR METHYL ESTER | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20030225145-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2003-12-04 | — | — | US | disclosed |
| US-6589969-B1 | A peroxisome proliferator activated receptor regulator containing a compound of formula (I) Because of having an effect of regulating PPAR, a compound of formula (I) is useful as a hypoglycemic agent, a hypolipidemic agent, a preventive | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1122255-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225145-A1 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | PPARA, PPARG, PPARD | PPARA 1/4885SLC22A12 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.