Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940504 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL6542059 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL6542187 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL14940505 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL3764487 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL3764484 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL9246837 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL29808745 | 0.98 | PDE4A (0.43) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL19952979 | 0.82 | PDE4A (0.59) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL258100 | 0.82 | PDE4A (0.59) | PDE4ALMNAUSP2SLCO1B1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10238599-B2 | Composition and method for treating congenital cytomegalovirus induced hearing loss | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-03-26 | — | — | US | disclosed |
| US-9919008-B2 | Method for treating age-related hearing loss (ARHL) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-03-20 | — | — | US | disclosed |
| US-9889156-B2 | Method for treating noise-induced hearing loss (NIHL) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-13 | — | — | US | disclosed |
| US-20180008537-A1 | Composition And Method For Treating Congenital Cytomegalovirus Induced Hearing Loss | UNIVERSITY OF UTAH | 2018-01-11 | — | — | US | disclosed |
| US-9770433-B2 | Composition and method for treating tinnitus | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170112803-A9 | Composition and Method for Treating Tinnitus | UNIV MICHIGAN REGENTS (US) | 2017-04-27 | — | — | US | disclosed |
| US-RE46372-E1 | Method for treating hearing loss | THE REGENTS OF THE UNIVERITY OF MICHIGAN (US) | 2017-04-25 | — | — | US | disclosed |
| US-20170095506-A1 | Method for Treating Noise-Induced Hearing Loss (NIHL) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-04-06 | — | — | US | disclosed |
| US-20170065632-A1 | Method for Treating Age-Related Hearing Loss (ARHL) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-03-09 | — | — | US | disclosed |
| US-20150374659-A1 | Composition and Method for Treating Tinnitus | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-12-31 | — | — | US | disclosed |
| US-6169187-B1 | CONVERTING PRECURSOR TO ASCORBIC ACID IN ORGANIC EXTRACTANT COMPOSITION COMPRISING SECONDARY OR TERTIARY ALKYLAMINE AND POLAR EXTRACTION ENHANCER, STRIPPING WITH AQUEOUS SOLUTION AT HIGHER TEMPERATURE | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-01-02 | — | — | US | disclosed |
| US-6037480-A | EXTRACTING ASCORBIC ACID WITH A WATER-IMMISCIBLE ORGANIC EXTRACTANT COMPRISING SECONDARY OR TERTIARY ALKYL AMINE AND POLAR EXTRACTION ENHANCER; SEPARATING ASCORBIC ACID-CONTAINING ORGANIC EXTRACTANT; STRIPPING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-03-14 | — | — | US | disclosed |
| EP-0941220-A1 | A PROCESS FOR RECOVERY OF ASCORBIC ACID | Yissum Research And Development Company Of The Hebrew University Of Jerusalem (IL) | 1999-09-15 | — | — | EP | disclosed |
| EP-0828725-A4 | PROCESS AND COMPOSITIONS FOR THE RECOVERY OF ASCORBIC ACID | YISSUM RES DEV CO (IL) | 1998-10-07 | — | — | EP | disclosed |
| WO-1998024777-A1 | A PROCESS FOR RECOVERY OF ASCORBIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1998-06-11 | — | — | WO | disclosed |
| WO-1996038433-A9 | PROCESS AND COMPOSITIONS FOR THE RECOVERY OF ASCORBIC ACID | — | 1998-05-22 | — | — | WO | disclosed |
| EP-0828725-A1 | PROCESS AND COMPOSITIONS FOR THE RECOVERY OF ASCORBIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1998-03-18 | — | — | EP | disclosed |
| WO-1997013761-A1 | A PROCESS FOR THE RECOVERY OF ASCORBIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1997-04-17 | — | — | WO | disclosed |
| WO-1996038433-A1 | PROCESS AND COMPOSITIONS FOR THE RECOVERY OF ASCORBIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1996-12-05 | — | — | WO | disclosed |
| EP-0682073-A2 | Polyolefin stabilization | PHILLIPS PETROLEUM COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |