Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 16/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6766189 | 0.88 | ATM (0.37) | F9F10PLAUF11PRSS1 | |
| Trifluoroacetic Acid SCHEMBL6768703 | 0.82 | F10 (0.42) | F9F10PLAUF11PRSS1 | |
| Trifluoroacetic Acid SCHEMBL6776292 | 0.78 | DPP4 (0.52) | DPP4PDE10APDE3BPDE3A | |
| SCHEMBL3896455 | 0.69 | PPARD (0.35) | — | |
| SCHEMBL3896456 | 0.69 | PPARD (0.35) | — | |
| Hydrochloric Acid SCHEMBL3898008 | 0.68 | PPARD (0.34) | — | |
| Hydrochloric Acid SCHEMBL3898010 | 0.68 | PPARD (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL6770800 | 0.67 | ROCK1 (0.38) | PDE10APDE3BPDE3AF9F10 | |
| Trifluoroacetic Acid SCHEMBL6770678 | 0.64 | F7 (0.33) | PDE10APDE3BPDE3AF9F10 | |
| Trifluoroacetic Acid SCHEMBL2544525 | 0.61 | ROCK1 (0.45) | F9PLAUF11PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |