SCHEMBL677626

SCHEMBL677626

CCCCC(=O)OC1=CC(=O)C=C2CC[C@@H]3[C@H]([C@@H](O)C[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO)[C@]21C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 11/20 0.61
NR3C1 P04150 5/20 0.61
NR3C2 P08235 5/20 0.61
PGR P06401 5/20 0.61
HSD17B10 Q99714 4/20 0.61
CYP2C19 P33261 3/20 0.61
SERPINA6 P08185 3/20 0.61
CYP3A4 P08684 2/20 0.61
AR P10275 2/20 0.61
ABCB11 O95342 1/20 0.61
TNF P01375 1/20 0.61
IL6 P05231 1/20 0.61
GLUL P15104 1/20 0.61
ADAM17 P78536 1/20 0.61
GPBAR1 Q8TDU6 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.58
KMT2A Q03164 3/20 0.58
MAPT P10636 2/20 0.58
SHBG P04278 1/20 0.58
NFKB1 P19838 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7986 0.98 HIF1A (0.60) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL28286516 0.98 HIF1A (0.60) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL7613028 0.98 HIF1A (0.60) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL7145318 0.98 HIF1A (0.60) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL7142740 0.98 HIF1A (0.60) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL11068491 0.96 HIF1A (0.62) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL945988 0.95 HIF1A (0.65) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL27977292 0.95 HIF1A (0.60) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL264554 0.94 HIF1A (0.64) HIF1ANR3C1NR3C2PGRHSD17B10
SCHEMBL27699939 0.94 HIF1A (0.57) HIF1ANR3C1NR3C2PGRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120154586-A Powder aerosol composition for inhalation, powder aerosol for inhalation, preparation method of powder aerosol for inhalation and powder aerosol for inhalation 上海臣邦医药科技股份有限公司 2025-06-17 CN claimed
CN-118662643-A Application of hormone medicine composition in preparation of medicine for treating osteoarthritis 中南大学湘雅医院 2024-09-20 CN claimed
CN-116940197-A Light emitting diode and preparation method thereof TCL科技集团股份有限公司 2023-10-24 CN claimed
CN-116098866-A Glucocorticoid fat emulsion for treating arthralgia, preparation method and application thereof 中南大学湘雅医院 2023-05-12 CN claimed
CN-116077669-A Glucocorticoid nano-lipid carrier for treating arthralgia, preparation method and application thereof 中南大学湘雅医院 2023-05-09 CN claimed
CN-116077465-A Nanometer preparation for joint pain relief, and preparation method and application thereof 中南大学湘雅医院 2023-05-09 CN claimed
CN-114698370-A Compounds and methods for treating cytokine release syndrome 里格尔药品股份有限公司 2022-07-01 CN claimed
CN-114685591-A Refining method and application of C1, 2-position dehydrosteroid compound 天津药业研究院股份有限公司 2022-07-01 CN claimed
WO-2022089499-A1 PREFERRED METHOD OF USING LEVALBUTEROL SULFATE FOR THE TREATMENT OF RESPIRATORY DISEASES 苏州君宁新药开发中心有限公司 2022-05-05 WO claimed
CN-114286679-A Methods of blocking or ameliorating cytokine release syndrome 里格尔药品股份有限公司 2022-04-05 CN claimed
CN-101060831-A Conveniently implantable sustained release pharmaceutical composition RAMSCOR INC (US) 2007-10-24 CN claimed
CN-1267087-C Pharmaceutical tablet PHARMACIA CORP (US) 2006-08-02 CN claimed
CN-1761487-A Dispersible formulations of anti-inflammatory agents PHARMACIA CORP (US) 2006-04-19 CN claimed
CN-1761486-A Dispersible pharmaceutical composition for treating mastitis and otic disorders PHARMACIA CORP (US) 2006-04-19 CN claimed
CN-1630512-A Pharmaceutical tablet PHARMACIA CORP (US) 2005-06-22 CN claimed
CN-1627938-A Pharmaceutical dosage form for transmucosal delivery PHARMACIA CORP (US) 2005-06-15 CN claimed
CN-1433396-A Pharmaceutical compounds NICOX SA (FR) 2003-07-30 CN claimed
CN-1420891-A Pharmaceutical compounds NICOX SA (FR) 2003-05-28 CN claimed
US-4765983-A INTESTINAL-SOLUBLE POLYMER AND MEDICAMENT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-08-23 US claimed
US-4478818-A Ocular preparation housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1984-10-23 US claimed