SCHEMBL6776722

SCHEMBL6776722

OCC1CCCCCC(O)C1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
GBA1 P04062 2/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
CHRM5 P08912 2/20 0.31
CYP1A2 P05177 1/20 0.31
ADRA2C P18825 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
EPHX1 P07099 2/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946480 0.97 TSHR (0.45) TSHRGBA1MGAMSICYP3A4
SCHEMBL2579684 0.92
SCHEMBL14724930 0.92
SCHEMBL14261873 0.92
SCHEMBL31645312 0.92
SCHEMBL898744 0.92
SCHEMBL2579686 0.92
Cyclohexanol SCHEMBL25424646 0.84 TSHR (0.56) TSHRGBA1CYP3A4CHRM5CYP1A2
SCHEMBL6562561 0.84 EPHX2 (0.37) GBA1CYP3A4CHRM5CYP1A2ADRA2C
SCHEMBL12055990 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6215031-B1 REDUCING 3-FORMYLCYCLOALKANONE OR 3-FORMYLCYCLOALKENONE;3-HYDROXYMETHYL-5,5-DIMETHYLCYCLOHEXANOL DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-10 US claimed
US-6673920-B2 REACTING AMIDES WITH ACETYLENES IN THE LIQUID PHASE IN THE PRESENCE OF BASIC ALKALI METAL COMPOUNDS AND OF A COCATALYST, WHICH COMPRISES USING AS THE COCATALYST DIOLS TO PREPARE N-ALKENYL-AMIDE BASF AKTIENGESELLSCHAFT (DE) 2004-01-06 US disclosed
US-20030036659-A1 Method for the production of n-alkenyl amides BASF AKTIENGESELLSCHAFT (DE) 2003-02-20 US disclosed
EP-1240140-A1 METHOD FOR THE PRODUCTION OF N-ALKENYL AMIDES BASF AKTIENGESELLSCHAFT (DE) 2002-09-18 EP disclosed
WO-2001046141-A1 METHOD FOR THE PRODUCTION OF N-ALKENYL AMIDES BASF AKTIENGESELLSCHAFT (DE) 2001-06-28 WO disclosed
US-6215031-B1 REDUCING 3-FORMYLCYCLOALKANONE OR 3-FORMYLCYCLOALKENONE;3-HYDROXYMETHYL-5,5-DIMETHYLCYCLOHEXANOL DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-10 US disclosed
EP-0895980-A1 3-HYDROXYMETHYLCYCLOALKANOLS AND PROCESS FOR PRODUCING THEM DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036659-A1 Method for the production of n-alkenyl amides NAT1, SAT1, AGPAT2 TSHR 3194/4885GBA1 467/4885MGAM 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.